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Lewin's GENES XI

Author(s): Jocelyn E. Krebs, PhD, Professor, University of Alaska, Anchorage
Elliott S. Goldstein, PhD, Associate Professor, Arizona State University
Stephen T. Kilpatrick, PhD, Associate Professor, University of Pittsburgh at Johnstown
  • ISBN-13: 9781449659851
  • Product With Access Code    940 pages      © 2014
Price: $270.95 US List
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“The molecular biology class I took as an undergraduate student used GENES VI, and I have always considered it one of the best books I used as a student.

-Dr. Matthew Stern, Winthrop University

Molecular Biology is a rapidly advancing field with a constant flow of new information and cutting-edge developments that impact our lives. Lewin's GENES has long been the essential resource for providing the teaching community with the most modern presentation to this dynamic area of study. GENES XI continues this tradition by introducing the most current data from the field, covering gene structure, sequencing, organization, and expression.  It has enlisted a wealth of subject-matter experts, from top institutions, to provide content updates and revisions in their individual areas of study. A reorganized chapter presentation provides a clear, more student-friendly introduction to course material than ever before.

  • Updated content throughout to keep pace with this fast-paced field.
  • Reorganized chapter presentation provides a clear, student-friendly introduction to course material.
  • Expanded coverage describing the connection between replication and the cell cycle is included, and presents eukaryotes as well as prokaryotes.
  • Available with new online Molecular Biology Animations.
  • Online access code for the companion website is included with every new book. The companion website offers numerous study aids and learning tools to help students get the most out of their course.
  • Instructor's supplements include: PowerPoint Image Bank, PowerPoint Lecture Slides, and Test Bank.

Applicable Courses

Written for the upper-division undergraduate or graduate Molecular Biology course, offered at the college and university level, within the departments of biology, molecular & cellular biology, and biochemistry.

Part  1  Genes and Chromosomes
  Chapter  1  Genes Are DNA
  Chapter  2  Genes Encode RNAs and Polypeptides
  Chapter  3  Methods in Molecular Biology and Genetic Engineering
  Chapter  4  The Interrupted Gene
  Chapter  5  The Content of the Genome
  Chapter  6  Genome Sequences and Gene Number
  Chapter  7  Clusters and Repeats
  Chapter  8  Genome Evolution
  Chapter  9  Chromosomes
  Chapter  10  Chromatin
Part  2  DNA Replication and Recombination
  Chapter  11  Replication Is Connected to the Cell Cycle
  Chapter  12  The Replicon: Initiation of Replication
  Chapter  13  DNA Replication
  Chapter  14  Extrachromosomal Replicons
  Chapter  15  Homologous and Site-Specific Recombination
  Chapter  16  Repair Systems
  Chapter  17  Transposable Elements and Retroviruses
  Chapter  18  Somatic Recombination and Hypermutation in the Immune System
Part  3  Transcription and Posttranscriptional Mechanisms
  Chapter  19  Prokaryotic Transcription
  Chapter  20  Eukaryotic Transcription
  Chapter  21  RNA Splicing and Processing
  Chapter  22  mRNA Stability and Localization
  Chapter  23  Catalytic RNA
  Chapter  24  Translation
  Chapter  25  Using the Genetic Code
Part  4  Gene Regulation
  Chapter  26  The Operon
  Chapter  27  Phage Strategies
  Chapter  28  Eukaryotic Transcription Regulation
  Chapter  29  Epigenic Effects Are Inherited
  Chapter  30  Regulatory RNA

Jocelyn E. Krebs, PhD-Professor, University of Alaska, Anchorage

Jocelyn E. Krebs received a B.A. in Biology from Bard College, Annandale-on-Hudson, New York, and a Ph.D. in Molecular and Cell Biology from the University of California, Berkeley. For her Ph.D. thesis, she studied the roles of DNA topology and insulator elements in transcriptional regulation. She performed her postdoctoral training as an American Cancer Society Fellow at the University of Massachusetts Medical School in the laboratory of Dr. Craig Peterson, where she focused on the roles of histone acetylation and chromatin remodeling in transcription. In 2000, Dr. Krebs joined the faculty in the Department of Biological Sciences at the University of Alaska, Anchorage, where she is now a Full Professor. Her most recent research focus has been on the role of the Williams syndrome transcription factor (one of the genes lost in the human neurodevelopmental syndrome Williams syndrome) in early embryonic development in the frog Xenopus. She teaches courses in introductory biology, genetics, and molecular biology for undergraduates, graduate students, and first-year medical students. She also teaches courses on the molecular biology of cancer and epigenetics. Although working in Anchorage, she lives in Portland, Oregon, with her wife and two sons, a dog, and three cats. Her nonwork passions include hiking, gardening, and fused glass work.


Additional Titles by this Author

Elliott S. Goldstein, PhD-Associate Professor, Arizona State University

Elliott S. Goldstein earned his B.S. in Biology from the University of Hartford in Connecticut and his Ph.D. in Genetics from the University of Minnesota, Department of Genetics and Cell Biology. Following this, he was awarded an NIH Postdoctoral Fellowship to work with Dr. Sheldon Penman at the Massachusetts Institute of Technology. After leaving Boston, he joined the faculty at Arizona State University in Tempe, Arizona, where he is an Associate Professor, Emeritus, in the Cellular, Molecular, and Biosciences program in the School of Life Sciences and in the Honors Disciplinary Program. His research interests are in the area of molecular and developmental genetics of early embryogenesis in Drosophila melanogaster. In recent years, he has focused on the Drosophila counterparts of the human protooncogenes jun and fos. His primary teaching responsibilities are in the undergraduate general genetics course as well as the graduate-level molecular genetics course. Dr. Goldstein lives in Tempe with his wife, his high school sweetheart. They have three children and two grandchildren. He is a bookworm who loves reading as well as underwater photography. His pictures can be found at

Additional Titles by this Author

Stephen T. Kilpatrick, PhD-Associate Professor, University of Pittsburgh at Johnstown

Stephen T. Kilpatrick received a B.S. in Biology from Eastern College (now Eastern University) in St. Davids, Pennsylvania, and a Ph.D. from the Program in Ecology and Evolutionary Biology at Brown University. His thesis research was an investigation of the population genetics of interactions between the mitochondrial and nuclear genomes of Drosophila melanogaster. Since 1995, Dr. Kilpatrick has taught at the University of Pittsburgh at Johnstown in Johnstown, Pennsylvania, where he is currently chair of the Department of Biology. His regular teaching duties include undergraduate courses in introductory biology for biology majors and advanced undergraduate courses in genetics (for both majors and nursing students), evolution, and molecular genetics. He has also supervised a number of undergraduate research projects in evolutionary genetics. Dr. Kilpatrick’s major professional focus has been in biology education. He has participated in the development and authoring of ancillary materials for several introductory biology, genetics, and molecular genetics texts and online educational review sites as well as writing articles for educational reference publications. For his classes at Pitt-Johnstown, Dr. Kilpatrick has developed many active learning exercises in introductory biology, genetics, and evolution. Dr. Kilpatrick resides in Johnstown with his wife and four cats. Outside of scientific interests, he enjoys music, literature, and theater.

  • Lewin’s GENES XI is the best molecular biology textbook with a high reputation. It is well written, up to date, and internationally adopted…The key strengths are the comprehensiveness. Almost every aspect of genes is included in the textbook.”

    –Dr. Zhiming Liu, Eastern New Mexico University

  • “The molecular biology class I took as an undergraduate student used GENES VI, and I have always considered it one of the best books I used as a student.”

    -Dr. Matthew Stern, Winthrop University

The following instructor resources are available to qualified instructors for download

ISBN-13: 9781449659851

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