Science in Medicine: The JCI Textbook of Molecular Medicine is a collection of acclaimed articles published in the Journal of Clinical Investigation during the Journal’s tenure at Columbia University. The society that publishes the JCI, the American Society for Clinical Investigation (ASCI), is an honor society of physician scientists, representing those who are at the forefront of translating findings in the laboratory to the advancement of clinical practice. This textbook brings together state-of-the-art reviews written by the world's leading authorities, including many ASCI members. The reviews examine the molecular mechanisms underlying a wide array of diseases and disorders affecting all major organ systems. The fundamentals of the organ or physiological systems in question are presented alongside the underlying genetic or physiological abnormalities that result in disease. This text illustrates the translation of basic scientific knowledge into the current practice of clinical medicine. The reviews provide an authoritative and comprehensive overview by building on known scientific concepts and treatment of human disease while exploring where these advances might take medicine over the next decade. The book is a valuable resource for medical students, graduate students, house staff, attending and practicing physicians, and biomedical researchers.
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Features & Benefits
Science in Medicine goes beyond introductory textbooks of basic clinical medicine to present a more sophisticated, in-depth, and multi-layered view of known mechanisms of disease in print and electronic format.
The text examines our understanding of disease mechanisms for an array of over 140 diseases and disorders affecting all major organ systems.
Written with the general, non-specialist JCI readership in mind, the text is broad and all-inclusive, outlining the fundamentals of the organ or other physiologic systems in question and proceeding to examine the underlying genetic of physiological abnormalities that result in disease. In cases where significant therapeutic advances have been made that are currently available in the clinic or in clinical trials, the fundamentals of drug action are examined in greater detail.
The text incorporates an explosion of new topics relevant to global public health such as the SARS virus, improved anthrax vaccines, and science, policy, and ethics of stem cell use.
Individual reviews are concise, accessible, and most often written as a self-contained treatment and focus on biological findings that are relevant to standard or experimental clinical practice.
This text is appropriate for graduate students, first and second year medical students, and allied health students, in courses throughout the curriculum of medicine and allied health, specifically courses that focus on metabolism and endocrinology.
American Society for Clinical Investigation