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Essentials of Molecular Biology, Fourth Edition

Author(s): George M. Malacinski, Indiana University, Indiana
  • ISBN-13: 9780763740115
  • ISBN-10:076374011X
  • Paperback    491 pages      © 2003
Price: $313.95 US List
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Essentials of Molecular Biology, Fourth Edition focuses on the fundamental aspects of molecular structure and function by reviewing key features and along the way, capsulizing them as a series of concise concepts. Thus, students are encouraged to place the reductionist knowledge of molecular biology into broad contexts and thereby develop both academic and personal meaning for this discipline.

Features & Benefits

A layering approach to knowledge construction is employed, developing complexity chapter-by-chapter, rather than presenting a series of detail-laden descriptions all at once.

The revision of Essentials of Molecular Biology has avoided expansion, and thereby continued to emphasize its most important virtue -- it captures the essence of each major aspect of the discipline of molecular biology, from review of structure to discussion of proteomics!

Genomics, bioinformatics, and proteomics chapter -- Cutting-edge research strategies are reviewed, for the first time in a molecular biology textbook!

A Postscript has been added that reviews the most surprising developments in molecular biology over the past two decades and dares to look ahead to potential discoveries. The Prologue also provides tips for students who want to continue their study of molecular biology.

The content and format were extensively field tested by hundreds of undergraduate students at Indiana University throughout the revision process.

Chapter Features:

  • Reader-friendly prose - Extensive "field testing" by students has generated very "readable" prose 
  • Welcome opening  chapter - Diminishes "intimidation" factor for many biology majors afraid of "chemical" biology 
  • Farewell closing - Invites students to consider a career in molecular biology 
  • Learning Guides - At end of book a guide to student learning styles encourages students to explore the way they learn complex phenomena 
  • Progression diagrams & Concise concepts - Each chapter is punctuated with "key concepts" which help students build a "big picture"


Chapter 1        Welcome to Molecular Biology

PART I              The Structure of Proteins, Nucleic Acids, and Macromolecular Complexes
Chapter 2        Macromolecules
Chapter 3        Nucleic Acids
Chapter 4        The Physical Structure of Protein Molecules
Chapter 5        Macromolecular Interactions and the Structure of Complex Aggregates

PART II             Function of Macromolecules
Chapter 6        The Genetic Material
Chapter 7        DNA Replication
Chapter 8        Transcription
Chapter 9        Translation
Chapter 10      Mutations, Mutagenesis, and DNA Repair

PART III           Coordination of Macromolecular Function in Cells
Chapter 11      Regulation of Gene Activity in Prokaryotes
Chapter 12      Regulation of Gene Activity in Eukaryotes
Chapter 13      Genomics and Proteomics Drive Information-Age Biology

PART IV            Experimental Manipulation of Macromolecules
Chapter 14      Transposons, Plasmids, and Bacteriophage
Chapter 15      Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes
Chapter 16      Molecular Biology is Expanding Its Reach

Postscript to Your Review of Molecular Biology
Chemical Principles Important for Understanding Molecular Biology
List of Essential Concepts of Molecular Biology

Answers to Questions and Problems

George M. Malacinski-Indiana University, Indiana

George M. Malacinski, Professor of Biology, Indiana University 
As an undergraduate Prof. M studied biology and chemistry at Boston University. He did undergraduate research on the bacteriophage life cycle and became interested in the value of prokaryotic organisms for understanding fundamental life processes.  As a graduate student at Indiana University he researched phosphorus metabolism in bacteria.  For postdoctoral research (at the University of Washington-Seattle) he broadened his training by studying the developmental genetics of the mammalian pancreas.  Returning to  Indiana University as a faculty member he established a research program in the molecular genetics of early amphibian embryogenesis.  His research interests most recently have included the analysis of molecular regulatory mechanisms of early muscle cell differentiation.  He has taught Molecular Biology to undergraduates for the past 10 years.

The following instructor resources are available to qualified instructors for download

ISBN-13: 9780763740115

Instructor Manual

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