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Glioblastoma Multiforme

Author(s): James Markert, MD, University of Alabama at Birmingham Medical Center
Vincent T. DeVita Jr., MD, Yale University School of Medicine, New Haven, Connecticut
Steven A. Rosenberg, MD, PhD, National Cancer Institute
Samuel Hellman, MD, University of Chicago Pritzker School of Medicine, Chicago, Illinois
Details:
  • ISBN-13: 9780763726409
  • ISBN-10:0763726400
  • Hardcover    316 pages      © 2005
Price: International Sales $207.95 US List
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Overview

Treatment of malignant glioma remains a major challenge for neurosurgeons, neurologists, medical oncologists, and radiation oncologists caring for patients with these tumors. Glioblastoma multiforme, the most common type of brain tumor, is also the most deadly -- only five percent of patients or fewer will be alive at five years after diagnosis. This comprehensive new reference is edited by a renowned team consisting of a neurosurgeon, medical oncologist, oncologic surgeon, and radiation oncologist. The book provides basic researchers and clinicians with a contemporary review of the epidemiology, diagnosis, and treatment of glioblastoma multiforme, and also imparts to experienced investigators outside of the field sufficient background to apply their skills to the treatment of this deadly disease. Expert malignant glioma researchers and clinicians provide state-of-the-art chapters on important topics such as molecular genetic classification of glioblastoma, surgical management, stem cell therapy, chemotherapy, angiogenesis, and more.

ShowKey Features

Edited by a renowned team consisting of a neurosurgeon, medical oncologist, oncologic surgeon, and radiation oncologist.

Provides basic researchers and clinicians with a contemporary review of the epidemiology, diagnosis, and treatment of glioblastoma multiforme.

Presents experienced investigators outside of the field with sufficient background to apply their skills to the treatment of this deadly disease.

Contains state-of-the-art chapters on important topics such as molecular genetic classification of glioblastoma, surgical management, stem cell therapy, chemotherapy, angiogenesis, and more.

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ShowTable of Contents

Chapter 1. Astrocyte Differentiation States and Glioma Formation;

Chengkai Dai, Eric Holland

Chapter 2. Classification of Glioblastoma Multiforme in Adults by

Molecular Genetics; Ramsis Benjamin, Joanna Capparella, Alice Brown

Chapter 3. FAK Signaling in Anaplastic Astroctoma and Glioblastoma Tumors;   Meera Natarajan, Timothy P. Hecker, Candece L. Gladson

Chapter 4. Angiogenesis in Glioma: Molecular Mechanisms and Roadblocks to Translation; Oliver Bogler, Tom Mikkelson

Chapter 5. Molecular Epidemiology of Glioblastoma;Kenneth D. Aldape, M. Fatih Okcu, Melissa L. Bondy

Chapter 6. Imaging Glioblastoma Multiforme;Sarah J. Nelson, Soonmee Cha

Chapter 7. Current Surgical Management of Glioblastoma; Stephen J. Hentschel, Frederick F. Lang

Chapter 8. Intraoperative Imaging in Glioblastoma Resection;   Vitale Siomin, Gene H. Barnett

Chapter 9. Role of Radiation Therapy and Radiosurgery in Glioblastoma Multiforme;   John B. Fiveash, Sharon A. Spencer

Chapter 10. Current Chemotherapy for Glioblastoma;   Ian F. Parney, Susan M. Chang

Chapter 11. Pediatric High-Grade Gliomas; Alyssa T. Reddy, John C. Wellons, III

Chapter 12. Long-term Survivors of Glioblastoma: Statistical Aberration or Important Unrecognized Molecular Subtype?; Donna Senger, J. Gregory Cairncross, Peter A. J. Forsyth

Chapter 13. Adoptive Immunotherapy for Malignant Glioma; Duane A. Mitchell, Peter E. Fecci, John H. Sampson

Chapter 14. Viral Therapy for the Treatment of Malignant Gliomas;Amish Shah, James M. Markert

Chapter 15. Gene Therapy for Human Malignant Brain Tumors;   Nikolai G. Rainov, Huan Ren

Chapter 16. Neural Stem Cell Biology: A Potential Tool for Improving Brain Tumor Therapies; Stephen Yip, Karen S. Aboody, Michael Burns, Jaime Imitola, John A. Boockvar, Jennifer Allport, Kook In Park, Yang D. Teng, Mahesh Lachyankar, Tracy McIntosh, Donald M. O’Rourke, Samia Koury, Ralph Weissleder, Peter M. Black, William Weiss, Evan Y. Snyder

 


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ShowAbout the Author(s)

James Markert, MD-University of Alabama at Birmingham Medical Center

Vincent T. DeVita Jr., MD-Yale University School of Medicine, New Haven, Connecticut

Dr. DeVita is Professor of Medicine and Professor of Epidemiology and Public Health at the Yale University School of Medicine in New Haven, CT. He is the former Director of the National Cancer Institute and developed the cure for Hodgkin's Disease and other lymphomas. He is the Director Emeritus at the Yale Cancer Center and has received numerous awards including the Mary and Albert Lasker Prize, the Medal of Honor from the American Cancer Society, the first Pezcoller Award from the European School of Oncology, the Armand Hammer Cancer Prize and the Surgeon General's Exemplary Service Medal. He recently was recognized with the 50th Anniversary Commemorative Award from the Leukemia Society of America and was the recipient of the first Saul Rosenberg Research Award from the Lymphoma Research Foundation of America. Dr. DeVita also served as co-chair of the National Cancer Legislative Advisory Committee for revising the National Cancer Act of 1971.

Additional Titles by this Author

Steven A. Rosenberg, MD, PhD-National Cancer Institute

Dr. Rosenberg received his B.A. and M.D. from the Johns Hopkins University, and he received a Ph.D. in biophysics from Harvard University. Following the completion of his surgical residency at the Peter Bent Brigham Hospital in Boston, MA, Dr. Rosenberg became chief of the Surgery Branch at the National Cancer Institute, Bethesda, MD in July 1974, a position he continues to hold now. His research interests have focused on studies of tumor immunology and the development of effective immunotherapies for the treatment of patients with cancer.

 

Samuel Hellman, MD-University of Chicago Pritzker School of Medicine, Chicago, Illinois

In the course of his career as a practitioner, teacher, investigator and leader in radiation oncology, Samuel Hellman, M.D., has advanced his specialty in too many ways to count. Although he is perhaps best known for advancing cancer treatment with his groundbreaking clinical research on malignant lymphomas and breast cancer, Dr. Hellman’s accomplishments at the institutions he served and with the students he mentored also have transformed and elevated the role of radiation oncology.  As a member of numerous external advisory committees, cancer-center boards, and research funding agencies, Dr. Hellman is a powerful advocate for radiology and the radiological sciences. 

 

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ShowReviews

  • "Glioblastoma Multiforme offers a discerning and critical view of dynamic fields of research as well as treatment. I recommend it especially to researchers with a specific interest in translation. It will be read with profit by researchers who seriously desire to enrich their minds with aspects of this complex disease in which they are not deeply rooted. Clinicians, including neuro-surgeons, neuro-oncologists, radiation oncologists, and allied health professionals, will benefit from a perusal of the research, which clearly is at the threshold of making dramatic inroads into the treatment of this devastating disease."

    --From review by John S. Yu
    Cedars-Sinai Medical Center in Neuro-Oncology
    (February 11, 2005)

    "This is an excellent book for neurology, oncology, and general medical libraries. Its contents would interest those in all areas of medicine dealing with the older population or involved with patients with glioblastoma multiforme."

    --Celso Agner, MD, MSc
    Albany Medical Center
    Doody Enterprises, Inc.
    December 2005

     

     

     

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