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Pediatric Stem Cell Transplantation

Author(s): Edited by Paulette Mehta, MD, University of Arkansas, Arkansas
Details:
  • ISBN-13: 9780763718558
  • ISBN-10:0763718556
  • Hardcover    486 pages      © 2004
Price: International Sales $258.95 US List
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Overview

The only comprehensive reference book on bone marrow and cell transplantation in children, Pediatric Stem Cell Transplantation addresses all the major dimensions — both scientific and clinical — of these life-saving procedures. In 24 concise chapters, written by world experts in pediatric hematology-oncology, immunology, pathology, and pediatrics, this book provides authoritative, timely, evidence-based information across the spectrum of related childhood illnesses. From histocompatibility and donor/patient management through nutrition, psychological/genetic counseling, and late effects/complications, Pediatric Stem Cell Transplantation offers complete coverage of the subject available in no other single source. It is an invaluable resource for all medical professionals who perform or support cell transplants in children.

ShowKey Features

24 comprehensive yet concise chapters, written by world-authority contributors.

Latest information on high dose chemotherapy and stem cell rescue for brain tumors.

State-of-the-art discussion of “mini-transplants.”

Unique chapter on umbilical cord blood transplantation.

Special summary of drugs used in pediatric transplantation. 

“Ethical Concerns” chapter provides latest thinking on informed consent, privacy, and commercial implications.

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ShowTable of Contents

Part I: Scientific Basis of Cell Transplantation in Children
Ch. 1: The Scientific Basis of Pediatric Bone Marrow Transplantation; Paulette Mehta
Ch. 2: Clinical and Research Background of Stem Cell Transplantation; Robert A. Good
Ch. 3: Finding Histocompatible Donors for Allotransplantation; Choon Kee Lee

Part II: Special Considerations
Ch. 4: Counseling Before Stem Cell Transplantation; Vicki L. Fisher
Ch. 5: Nutrition for the Child Undergoing Cell Transplantation; Indira Sahdev
Ch. 6: Pediatric Stem Cell Transplantation: Ethical Concerns; Puneet Cheema
Ch. 7: After Psychosocial Adjustment Stem Cell Transplantation; Allen C. Sherman
Ch. 8: Medically Indicated Banking of Sibling Donor Cord Blood; William Reed

Part III: Disease Specific Pediatric Cell Transplants
Ch. 9: Neuroblastoma; Joan Morris
Ch. 10: Stem Cell Transplantation for Ewing’s Sarcoma; Robert B. Marcus
Ch. 11: High Dose Chemotherapy and Stem Cell Rescue for Treatment of Brain Tumors; Naomi Moskowitz
Ch. 12: Acute Lymphoblastic Leukemia; Eric Sandler
Ch. 13: Stem Cell Transplantation for Patients with Acute Myelogenous Leukemia; Suneetha Challagundla
Ch. 14: Myelodysplastic Disorders and Related Diseases; Michael L. Nieder
Ch. 15: Metabolic Diseases; Charles Peters
Ch. 16: Hematopoietic Stem Cell Transplantation for Hemoglobinopathies; Lakshmanan Krishnamurti
Ch. 17: Hematopoietic Stem Cell Transplantation for Inherited Bone Marrow Failure Syndromes; Adrianna Vlachos

Part IV: Special Procedures
Ch. 18: Immune Ablative (mini) Transplants in Pediatrics; Morris Kletzel
Ch. 19: Umbilical Cord Blood Transplantation; Donna Wall
Ch. 20: Ex Vivo Expansion of Hematopoietic Stem Cells; Peter Shaw

Part V: Complications

Ch. 21: Immunotherapy Options for Relapse After BMT; John Levine
Ch. 22: Infectious Complications After Hematopoietic Cell Transplantation; John R.Wingard
Ch. 23: Graft-Versus-Host Disease After Stem Cell Transplantation in Children; Paulette Mehta
Ch. 24: Late Effects After Hematopoeitic Cell Transplantation; Jean E. Sanders


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ShowAbout the Author(s)

Edited by Paulette Mehta, MD-University of Arkansas, Arkansas

Dr. Paulette Mehta is professor of hematology oncology at the University of Arkansas for Medical Sciences and was previously Director of Pediatric Hematology Oncology and Bone Marrow Transplantation at the University of Florida, College of Medicine, in Gainesville, Florida. She co-directs a Fellowship program for trainees in hematology oncology and is principal investigator of many national protocols. She is presently involved in a long-term national longitudinal study on survivors of bone marrow transplantation.

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ShowReviews

  • "Dr. Mehta's vision...is to be commended."

    - Dr. Roderick Skinner
    Pediatric Hematology and Oncology
    December, 2004; 21(8)

     "A book long overdue for Pediatric Hematologists, Oncologists and Transplanters. This comprehensive text deals not only with the scientific basis of transplantation and the major diseases for which transplantation is used in pediatrics, but also covers issues of patient and minor donor counseling, ethics, identification of stem cell donors, cord blood banking and transplant complications. All who work with children considering or undergoing transplantation will find this text valuable."

    -Jean E. Sanders, M.D.
    Professor of Pediatrics, University of Washington
    Member, Fred Hutchinson Cancer Research Center
    Director, Pediatric Stem Cell Transplantation, FHCRC


    "Dr. Mehta has compiled a comprehensive scholarly treatise on stem cell transplantation in children. She reviews the evolving paradigms for the role of bone marrow transplantation and specifics for utilization of the procedure in settings ranging from leukemia to metabolic diseases to hemoglobinopathies. Donor issues, ethics, and the psychosocial adjustment of transplant recipients are discussed. This volume is certain to be consulted frequently by pediatric oncologists, immunologists, and consultants who care for these children."

    -Debra H. Fiser, M.D.
    Professor and Chair, Department of Pediatrics
    University of Arkansas for Medical Sciences

    "There are several excellent texts on hematopoietic cell transplantation. None to date have focused on pediatric issues. Yet many of the principles were developed in pediatrics and in no other group of patients have the advances in the field improved outcomes to the degree they have in pediatrics. This text is an excellent and needed contribution, with authoritative authors, a good measure of practical, up-to-date advice along with discussion of their scientific basis, and it provides comprehensive presentations of pediatric topics. This fills a gaping hole for a comprehensive resource needed by all transplant clinicians and scientists."

    -John R. Wingard, M.D.
    Price Eminent Scholar and Professor of Medicine
    Director, Blood and Marrow Transplant Program

    "This is a timely book focused on the pediatric indications and aspects of stem cell transplantation [covering] the important aspects of stem cell transplants…unique to pediatrics such as family support, psychosocial issues, cord blood cells, etc. These aspects are not usually addressed in generic transplant related books."

    -Doody’s Reviews

    Shalini Shenoy, MD

    Washington University School of Medicine

     

    Pediatric Stem Cell Transplantation is a scholarly, graduate-studies level text concerning the rapidly developing medical science and process of cell transplantation as a technology and treatment approach for use with children. An extremely comprehensive reference text…Pediatric Stem Cell Transplantation is especially recommended…”

     

    -The Midwest Book Review

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