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Oncogenes, Second Edition

Author(s): Geoffrey M. Cooper, PhD, Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts
Details:
  • ISBN-13: 9780867209372
  • ISBN-10:0867209372
  • Paperback    384 pages      © 1995
Price: International Sales $158.95 US List
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Overview

The study of oncogenes and tumor suppressor genes continues to be a fast-moving area of science. This authoritative text provides a conceptual framework which allows students and professionals to understand this complex field. It also serves as a comprehensive reference for scientists engaged in oncogene research. The second edition of this text details major advances and developments in the field, such as the identification of many new tumor suppressor genes and the striking progress in understanding signal transduction pathways leading to cell proliferation. Oncogenes, Second Edition, addresses the needs of advanced undergraduates, graduate students, medical students, physicians, and scientists by examining the current state of oncogene study and where future research may lead.

ShowTable of Contents

UNIT I: Introduction
1.The Cancer Cell
UNIT II: Viral Oncogenes
2. Tumor Viruses
3. Retroviral Oncogenes
4. The Origin of Retroviral Oncogenes
UNIT III: Cellular Oncogenes and Tumor Suppressor Genes
5. Identification of Cellular Oncogenes by Gene Transfer
6. Cellular Oncogene Targets for Retroviral Integration
7. Oncogenes and Chromosome Translocation
8. Amplification of Oncogenes in Tumors
9. Discovery of Tumor Suppressor Genes: The Retinoblastoma Prototype
10. Tumor Suppressor Genes in Human Neoplasms
11. Role of Oncogenes and Tumor Suppressor Genes
UNIT IV: Functions of Oncogenes and Tumor Suppressor Genes
12. Oncogenes and Growth Factors
13. Protein-Tyrosine Kinases and Growth Factor Receptors
14. Guanine Nucleotide Binding Proteins
15. Protein-Serine/Threonine Kinases
16. Transcription Factors
17. Pathways of Mitogenic Signal Transduction
18. Regulation of the Cell Cycle
19. Development, Differentiation, and Programmed Cell Death
UNIT V: Clinical Applications
20. New Prospects for Cancer Prevention and Treatment

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ShowAbout the Author(s)

Geoffrey M. Cooper, PhD-Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts

Additional Titles by this Author

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