Preface
Acknowledgements
SECTION I. INTRODUCTION
1. Toxicology and Its Roots as a Science
2. Chemical Properties and Information Resources on Hazardous Chemicals
3. Toxicity and the Factors That Modify Toxic Responses
4. Biological Poisons: Plant and Animal Toxins
5. Environmental Pollutants and Their Fate
SECTION II. TOXICOLOGY PRINCIPLES
6. Dose and Response
7. Absorption of Toxicants and Models of Disposition
8. Distribution, Storage, and Elimination of Toxicants
9. Biotransformation
10. Chemical-Induced Mutagenesis
11. Chemicals and Cancer
SECTION III. SYSTEMIC TOXICITY
12. Role of Immune System
13. Skin
14. The Liver and Kidneys
15. The Cardiovascular System
16. The Respiratory System
17. The Nervous System
SECTION IV. TOXICOLOGY PRACTICE
18. The Practice of Toxicology
19. Regulatory Considerations
20. Toxicity Testing
21. Use and Limitations of Product Labeling for Public Safety
22. Toxicology Principles in the Management of Acute Poisonings
23. Risk Assessment and the Perception of Risk
24. Making Informed Decisions
Glossary
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