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Protein Microarrays

Author(s): Mark Schena, PhD, TeleChem International, Inc.
Details:
  • ISBN-13: 9780763731274
  • ISBN-10:0763731277
  • Hardcover    469 pages      © 2005
Price: International Sales $245.95 US List
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Overview

"It appears that the FDA, Industry, and Academia have a common interest in the development and use of protein microarrays and of techniques for establishing microarray diagnostic performance. As this text indicates, there is a wide range of scientific talent and many ongoing projects being applied to the many issues integral to the successful implementation of this new area of science."

--From the Foreword by Joseph L. Hackett and Emanuel F. Petricoin

 

 

This dynamic new volume conceived and edited by Mark Schena features 24 cutting-edge chapters from the leading laboratories in the hot new field of protein microarrays. Dr. Schena, who published the first two papers on DNA microarrays in 1995 and 1996, extends his original vision of parallelism and miniaturization to advance the protein microarray field. This new area promises important breakthroughs in disease diagnostics and drug discovery, as well as basic research on protein expression, development, the immune system, aging, behavior, and other issues central to medicine. Protein Microarrays is the first comprehensive treatment of protein microarray technology and includes detailed descriptions of manufacturing methods, surface chemistry, detection strategies, and data analysis for antigen, antibody, and peptide microarray assays. The book also presents numerous biological applications and experimental protocols not available from any other source. Protein Microarrays is an exceptional treatise and essential reading for everyone in the microarray and proteomics fields.

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TABLE OF CONTENTS

Foreword by Joseph L. Hackett and Emanuel F. Petricoin

Chapter 1.  Principles of Protein Microarrays; Mark Schena

Chapter 2.  Novel Strategies in Protein Microarray Generation and Detection; Yee-Peng Rina Lue, Su-Yin Dawn Yeo, Lay-Pheng Tan, Mahesh Uttamchandani, Grace Yi-Jun Chen, and Shao Q. Yao

Chapter 3.  Practical Guide to Protein Microarrays: Assay Systems, Methods, and Algorithms; Mikhail Soloviev, Jon Terrett

Chapter 4.  Microarrays for the High-Throughput Analysis of Protein--Carbohydrate Interactions; William G. T. Willats

Chapter 5.  Protein Microarrays: Principles and Limitations; Victor N. Morozov

Chapter 6.  System-Oriented Proteomics Using Protein-Domain Microarrays; Alexsandra Espejo, Mark T. Bedford

Chapter 7.  Colorimetric Microarray Assays for Rheumatoid Arthritis using a Recombinant Proteome Library; Stewart J. Lebrun

Chapter 8.  Academic and Commercial Aspects of Protein Microarray Development; Seung-yong Seong

Chapter 9.  Analyzing Proteins and Protein Modifications with ArrayTube™ Antibody Microarrays; Stefan Wölfl, Annegret Dummer, Larissa Pusch, Marina Pfalz, Lin Wang, Joachim H.   Clement, Ines Leube, Ralf Ehricht

Chapter 10.  Non-contact Dispensing for Protein Microarrays; Thomas C. Tisone, John L. Tonkinson

Chapter 11.  High Speed, High Efficiency Protein Printing by BioLP™; Bradley R. Ringeisen, Jason A. Barron, David B. Krizman

Chapter 12.  Putting the “Bio” in Biochips: Capture Agents for Protein Microarray Expression Profiling Platforms; David S. Wilson, Michael L. Phelan, Steffen Nock

Chapter 13.  Protein Biochips for the Profiling of Allergen-Specific Antibodies; Christian Harwanegg, Susanne Spitzauer, Rudolf Valenta, Manfred W. Mueller, Reinhard Hiller

Chapter 14.  Solid Supports for Protein Microarrays and Related Devices; Wlad Kusnezow, Timo Pulli, Olaf Witt, Jörg D. Hoheisel

Chapter 15.  Protein Microarrays for Biosensor Applications; Michael G. Weller

Chapter 16.  Technological Aspects of Protein Microarrays and Nanoarrays; Fan-Gang Tseng, Shih-Chang Lin, Da-Jen Yao, Haimei Huang, Ching-Chang Chieng

Chapter 17.  Mega-Dense Nanoarrays: The Challenge of Novel Antibody Microarray Formats; Christer Wingren, Lars Montelius, Carl A. K. Borrebaeck

Chapter 18.  INFINITI™ System: An Automated Multiplexing Protein Microarray Platform; Anupam Talapatra, Vijay Mahant, Fareed Kureshy, Gary Hardiman

Chapter 19.  Protein Microarrays for Analysis of Antibody Responses in Animals and Humans; Paul J. Utz, Lawrence Steinman, William H. Robinson

Chapter 20.  G Protein–Coupled Receptor Microarrays: A Versatile Tool for Drug Discovery; Ye Fang, Yulong Hong, Jinlin Peng, Joydeep Lahiri

Chapter 21.  Proteome-Scale Analysis of the Immune Response Against Pathogenic Microorganisms; Tito Bacarese-Hamilton, Julian Gray, Andrea Crisanti

Chapter 22. Development of Protein Microarrays for Drug Discovery; Jens O. Koopmann, Michael B. McAndrew, Jonathan M. Blackburn

Chapter 23. Development and Applications of Functional Protein Microarrays; James Ball, Barry Schweitzer, Paul Predki, Michael Snyder

Chapter 24. Enabling Tools for Protein Microarrays; Todd Martinsky


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ShowAbout the Author(s)

Mark Schena, PhD-TeleChem International, Inc.

Dr. Schena received his B.A. in biochemistry from the University of California, Berkeley, his Ph.D. in biochemistry from the University of California, San Francisco and studied as a postdoctoral fellow in the department of biochemistry at Stanford University.  Dr. Schena published the first two papers on DNA microarrays in 1995 and 1996, wrote the first two books on microarrays, edited the only textbook on the subject, and has given more than 100 lectures in 20 countries to advance the science worldwide.  Dr. Schena is currently a visiting scholar in the ArrayIt Life Sciences Division at TeleChem International, Inc. 

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